Ventoxen Tablets 100mg

Generic Name: Venclexta

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Regular price Rs.90,000.00 PKR inc. VAT

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Product Description

Product Name: Ventoxen Tablets 100mg

Product Form: Tablets

Pack Size: 60's

Manufactured By: Everest Pharmaceuticals

Used For:

Venclexta is an oral anticancer medication that works by inhibiting the protein BCL-2, which helps cancer cells survive. It is used to treat certain types of blood cancers, including:

  • Chronic Lymphocytic Leukemia (CLL): Used in adult patients with or without the deletion of chromosome 17p.
  • Small Lymphocytic Lymphoma (SLL): A type of non-Hodgkin lymphoma.
  • Acute Myeloid Leukemia (AML): Often in combination with other therapies for patients who are ineligible for intensive chemotherapy.

Side Effects:

Common side effects of Venclexta include:

  • Nausea
  • Diarrhea
  • Fatigue
  • Constipation
  • Upper respiratory tract infection
  • Fever
  • Decreased appetite

Serious side effects may include:

  • Tumor Lysis Syndrome (TLS): A potentially life-threatening condition caused by the rapid breakdown of cancer cells. Signs include kidney problems, low blood calcium, or elevated potassium and uric acid levels.
  • Neutropenia: A significant decrease in white blood cells, increasing infection risk.
  • Infections: Serious bacterial, fungal, or viral infections can occur.
  • Anemia or thrombocytopenia: Low red blood cell or platelet levels may lead to fatigue, bruising, or bleeding.

Precautions:

  • Tumor Lysis Syndrome (TLS): Patients with a high tumor burden are at increased risk. Preventive measures, such as hydration and medications like allopurinol, may be prescribed.
  • Blood Counts: Regular blood tests are essential to monitor white blood cells, platelets, and hemoglobin levels.
  • Infection Risk: Venclexta weakens the immune system, increasing susceptibility to infections. Promptly report symptoms such as fever, chills, or unusual fatigue.
  • Drug Interactions: Avoid medications or substances that inhibit or induce CYP3A enzymes (e.g., certain antifungals, antibiotics, or grapefruit), as they can alter Venclexta levels.
  • Pregnancy and Breastfeeding: Venclexta can harm an unborn baby and should not be used during pregnancy. Effective contraception is recommended during treatment and for a period after discontinuation. Breastfeeding is not advised during treatment.
  • Renal or Hepatic Impairment: Use with caution in patients with kidney or liver conditions, as these may affect drug metabolism and clearance.

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