Soranib Tablets 200mg

Product Description

Product Name: Soranib Tablets 200mg

Product Form: Tablets

Pack Size: 30's

Manufactured By: Cipla Pharmaceuticals

Used For:

1. Hepatocellular Carcinoma (HCC):
   • First-line treatment for advanced liver cancer.
2. Renal Cell Carcinoma (RCC):
   • Used in advanced kidney cancer, often as second-line therapy.
3. Differentiated Thyroid Carcinoma (DTC):
   • Approved for use in metastatic, radioactive iodine-refractory thyroid cancer.

Side Effects:

1. Common Side Effects:
   • Diarrhea, nausea, vomiting, or abdominal pain.
   • Hand-foot syndrome (palmar-plantar erythrodysesthesia).
   • Fatigue, weight loss, or decreased appetite.
   • Rash, itching, or hair thinning.
   • Hypertension (high blood pressure).
2. Serious Side Effects:
   • Hepatotoxicity: Elevated liver enzymes; regular monitoring is required.
   • Cardiac Issues: Ischemic events like myocardial infarction or angina.
   • Bleeding Risk: Increased risk of hemorrhage.
   • Gastrointestinal Perforation: Rare but life-threatening.
   • Wound Healing Complications: Slowed healing in patients undergoing surgery.

Precautions:

1. Monitoring:
   • Regular liver function tests and blood pressure monitoring.
   • Monitor for signs of bleeding, infection, or cardiac ischemia.
2. Pregnancy and Breastfeeding:
   • Contraindicated in pregnancy due to teratogenic effects.
   • Breastfeeding is not recommended during treatment.
3. Drug Interactions:
   • Avoid with strong CYP3A4 inducers or inhibitors, as they may alter sorafenib levels.
   • Use cautiously with anticoagulants or NSAIDs due to increased bleeding risk.
4. Dietary Considerations:
   • Take on an empty stomach (1 hour before or 2 hours after meals).