Siroall Tablets 1mg

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Regular price Rs.18,516.00 PKR inc. VAT

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Product Description

Product Name: Siroall Tablets 1mg

Product Form: Tablets

Pack Size: 30's

Manufactured By: Allmed Laboratories

Used For:

  • Organ Transplant Rejection Prevention: Sirolimus is primarily prescribed to prevent kidney transplant rejection. It may also be used off-label for other organ transplants in some cases.
  • Certain Rare Diseases: Sirolimus may be prescribed for rare disorders like lymphangioleiomyomatosis (LAM), a lung disease that primarily affects women.
  • Cancer: Because it inhibits cell growth, sirolimus is being studied as a potential treatment for certain cancers and as a part of cancer therapies.

Side Effects:

Common side effects include:

  • Mouth ulcers or sores
  • Increased risk of infections due to immunosuppression
  • Elevated cholesterol and triglycerides in the blood
  • Nausea, diarrhea, and stomach discomfort
  • Acne or rash
  • Anemia and other blood disorders
  • Swelling in the arms, legs, or other areas
  • Delayed wound healing

Serious side effects include:

  • Increased risk of infections: Sirolimus can significantly weaken the immune system, making infections more likely.
  • Lung issues: Such as interstitial lung disease, which can cause difficulty breathing, cough, or chest pain.
  • Kidney issues: Although sirolimus is used in kidney transplants, it can still cause or worsen kidney problems, especially when used with other immunosuppressants.
  • Liver dysfunction: It may cause elevated liver enzymes and, in rare cases, liver damage.
  • Lymphomas and other cancers: Long-term use may increase the risk of developing certain cancers due to its immunosuppressive effects.

Precautions:

  • Infection risk: Since sirolimus suppresses the immune system, patients should take extra precautions to avoid infections, practice good hygiene, and promptly report any signs of infection to their healthcare provider.
  • Kidney and liver function monitoring: Regular blood tests are needed to monitor kidney and liver function, as well as sirolimus blood levels, to ensure appropriate dosing and avoid toxicity.
  • Avoid live vaccines: Live vaccines should not be administered to patients on sirolimus, as their immune system may not be able to handle it.
  • Pregnancy and breastfeeding: Sirolimus is generally not recommended during pregnancy, as it may harm a developing fetus. Women should use effective contraception while on this medication. Its safety during breastfeeding is unknown, so it’s advised to avoid breastfeeding while on sirolimus.

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