Product Description

Product Name: Saveril Tablets 100mg

Product Form: Tablets

Pack Size: 50's

Manufactured By: Genetics Pharmaceuticals

Used For:

Treatment-Resistant Schizophrenia: Clozapine is often prescribed when other antipsychotics have been ineffective in managing symptoms.
Reduction of Suicidal Behavior: It is sometimes used in patients with schizophrenia or schizoaffective disorder to reduce the risk of recurrent suicidal behavior.

Common Side Effects:
- Drowsiness and sedation
- Increased salivation (hypersalivation)
- Constipation
- Weight gain
Serious Side Effects:
- Agranulocytosis: A potentially life-threatening reduction in white blood cells, making patients susceptible to infections. Regular blood tests are mandatory to monitor this.
- Myocarditis and Cardiomyopathy: Inflammation of the heart muscle, which can be fatal if not detected early.
- Seizures: Clozapine may lower the seizure threshold, especially at higher doses.
- Orthostatic Hypotension: Sudden drop in blood pressure when standing, which can lead to fainting.
- Metabolic Syndrome: Increased risk of diabetes, high cholesterol, and weight gain.

Blood Monitoring: Regular blood tests (usually weekly to monthly) are required to monitor white blood cell counts due to the risk of agranulocytosis.
Heart Health: Patients should be monitored for signs of myocarditis, especially in the initial months of treatment.
Seizure Risk: Patients with a history of seizures should use Clozapine with caution.
Smoking and Caffeine: Smoking can reduce the effectiveness of Clozapine, and caffeine can increase its levels in the blood, so lifestyle adjustments may be needed.
Pregnancy and Breastfeeding: The safety of Clozapine in pregnancy is not well-established; it should only be used if clearly needed and under the guidance of a healthcare provider.