Platinex Injection 50ml

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Product Description

Product Name: Platinex Injection 50ml

Product Form: Injection

Pack Size: 1's

Manufactured By: Khandelwal Laboratories

Used For:

Cisplatin is used to treat a variety of cancers, including:

  1. Testicular cancer
  2. Ovarian cancer
  3. Bladder cancer
  4. Lung cancer (both small-cell and non-small-cell types)
  5. Head and neck cancers
  6. Esophageal cancer
  7. Cervical cancer
  8. Sarcomas
  9. Brain tumors (such as glioblastoma)

Side Effects:

Cisplatin is associated with significant side effects, which vary in severity:

Common Side Effects:

  • Nausea and vomiting (severe; often requires antiemetic medications)
  • Kidney toxicity (nephrotoxicity): Can cause kidney damage; hydration and protective agents (e.g., amifostine) are often used.
  • Hearing loss (ototoxicity): Can lead to tinnitus or permanent hearing impairment.
  • Peripheral neuropathy: Numbness, tingling, or pain in hands and feet.
  • Bone marrow suppression: Leading to anemia, leukopenia, and thrombocytopenia.
  • Fatigue
  • Loss of appetite

Serious Side Effects (Less Common):

  • Severe allergic reactions (e.g., anaphylaxis)
  • Liver toxicity
  • Electrolyte imbalances (e.g., low magnesium or potassium levels)
  • Cardiovascular issues (e.g., arrhythmias, rare but possible)

Precautions:

  1. Renal Function:
    • Regular monitoring of kidney function (creatinine levels, GFR) is critical.
  2. Hydration:
    • Patients must be well-hydrated before, during, and after treatment to reduce nephrotoxicity.
  3. Hearing Monitoring:
    • Audiometric testing is recommended, especially for patients receiving high doses or multiple cycles.
  4. Electrolyte Monitoring:
    • Frequent checks for magnesium, potassium, and calcium levels, as cisplatin can cause imbalances.

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