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Natrilam MR Tablets 5-1.5mg

Generic Name: Amlodipine and Indapamide

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Rs.599.00 PKR inc. VAT

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Product Description

Product Name: Natrilam MR Tablets 5-1.5mg

Product Form: Tablets

Pack Size: 30s

Manufactured By: Servier

Used For:

  1. Hypertension (High Blood Pressure): Both components work together to lower blood pressure. Amlodipine relaxes blood vessels, while Indapamide reduces fluid retention, which decreases the volume of blood and pressure on the vessel walls.
  2. Prevention of Cardiovascular Events: By managing high blood pressure, Natrilam helps lower the risk of serious cardiovascular issues like heart attacks and strokes.

Side Effects:

Side effects may arise from either amlodipine or indapamide. Common and serious side effects include:

  • Common side effects:

    • Amlodipine-related:
      • Swelling of the ankles or feet (edema)
      • Flushing (warmth or redness in the face)
      • Dizziness or lightheadedness
      • Headache
    • Indapamide-related:
      • Increased urination
      • Dizziness (especially when standing up quickly)
      • Muscle cramps or weakness (due to electrolyte imbalance)
      • Fatigue

  • Serious side effects:

    • Amlodipine-related:
      • Severe low blood pressure (hypotension)
      • Worsening of angina (chest pain) or heart failure in rare cases
      • Irregular heartbeats or palpitations
      • Allergic reactions (swelling, rash, difficulty breathing)
    • Indapamide-related:
      • Severe dehydration or electrolyte imbalances (such as low potassium or sodium levels)
      • Kidney problems (swelling in the legs, reduced urine output)
      • Allergic reactions

Precautions:

  1. Swelling (Amlodipine): Amlodipine can cause swelling in the legs or ankles. If this becomes problematic, consult your healthcare provider for possible dosage adjustments or additional treatments.

  2. Electrolyte Imbalance (Indapamide): Indapamide can cause electrolyte disturbances (such as low potassium or sodium), so regular blood tests may be needed to monitor electrolyte levels.

  3. Low Blood Pressure: Since both components lower blood pressure, there is a risk of hypotension (low blood pressure), especially when standing up suddenly (orthostatic hypotension). Rise slowly from sitting or lying positions to reduce dizziness.

  4. Kidney and Liver Function: Indapamide can affect kidney function, and Amlodipine is metabolized by the liver. Regular monitoring of kidney and liver function is recommended, especially for individuals with pre-existing conditions affecting these organs.

  5. Pregnancy and Breastfeeding: Natrilam is not recommended during pregnancy, especially in the first trimester, due to the potential risks to the fetus. It should also be avoided during breastfeeding unless prescribed by a healthcare provider.

  6. Heart Conditions: In rare cases, amlodipine can worsen chest pain (angina) or cause heart failure. Report any new or worsening symptoms to your doctor immediately.

  7. Alcohol: Consuming alcohol while taking Natrilam may increase the risk of side effects like dizziness and low blood pressure.

  8. Drug Interactions: This medication can interact with other antihypertensive drugs, non-steroidal anti-inflammatory drugs (NSAIDs), or medications that affect electrolytes. Inform your healthcare provider of all medications or supplements you are taking.

  9. Use in the Elderly: Elderly individuals may be more sensitive to the effects of Natrilam, especially regarding blood pressure and electrolyte imbalances. Close monitoring and potential dose adjustments may be necessary.