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Himont Laboratories

Narcogen Tablets 100mg

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Product Description

Product Name: Narcogen Tablets 100mg

Product Form: Tablets

Pack Size: 20's

Manufactured By: Himont Laboratories

Used For:

Nimesulide is a nonsteroidal anti-inflammatory drug (NSAID) that is primarily used for its analgesic (pain-relieving), anti-inflammatory, and antipyretic (fever-reducing) effects. It is commonly prescribed for:

  1. Pain Relief: Used to manage acute pain conditions, such as headaches, dental pain, post-surgical pain, or musculoskeletal pain.
  2. Osteoarthritis: Helps reduce pain and inflammation associated with osteoarthritis.
  3. Primary Dysmenorrhea: Commonly prescribed to relieve menstrual pain.
  4. Fever: Used to reduce fever in certain conditions (though not as commonly as other NSAIDs).

Side Effects:

Common and serious side effects of nimesulide include:

  • Common side effects:

    • Nausea
    • Vomiting
    • Diarrhea
    • Dizziness
    • Heartburn or indigestion
    • Rash or itching
    • Headache

  • Serious side effects:

    • Liver toxicity: One of the major concerns with nimesulide is its potential to cause liver damage (hepatotoxicity), which can lead to liver failure in rare cases.
    • Kidney damage: Long-term use can impair kidney function.
    • Gastrointestinal issues: Stomach ulcers, bleeding, or perforation, especially with long-term use.
    • Allergic reactions: Skin reactions like rashes, hives, or even more serious conditions such as Stevens-Johnson syndrome.
    • Blood disorders: Rarely, it can cause platelet disorders or increase the risk of bleeding.
    • Heart problems: Similar to other NSAIDs, nimesulide may increase the risk of cardiovascular events like heart attacks or strokes, though the risk is generally lower than with long-term use.

Precautions:

  1. Liver Toxicity Risk: Nimesulide has been associated with liver toxicity, which is why it is banned in several countries for long-term use. In places where it is available, it is generally prescribed for short-term use only (typically no longer than 15 days), and patients are monitored for liver function. Anyone with pre-existing liver conditions should avoid using this medication.

  2. Kidney Function: As with other NSAIDs, nimesulide can reduce kidney function, so it should be used cautiously in individuals with kidney disease or those at risk for kidney impairment.

  3. Gastrointestinal Risk: Nimesulide can cause gastrointestinal ulcers and bleeding, particularly with prolonged use. It should be taken with food to minimize stomach irritation. People with a history of gastrointestinal issues should avoid using this drug.

  4. Cardiovascular Risk: While it is less likely to increase cardiovascular risks compared to some other NSAIDs, it should still be used with caution in individuals with heart conditions, high blood pressure, or a history of cardiovascular disease.

  5. Pregnancy and Breastfeeding: Nimesulide is not recommended during pregnancy, especially in the third trimester, as it may harm the fetus. It is also contraindicated during breastfeeding.

  6. Children: Nimesulide is generally contraindicated in children under 12 years of age due to the risk of liver toxicity.

  7. Drug Interactions: Nimesulide can interact with other medications, including blood thinners (anticoagulants), other NSAIDs, corticosteroids, and drugs affecting liver enzymes (such as alcohol or certain antibiotics), increasing the risk of adverse effects.

  8. Short-Term Use Only: Nimesulide should be used for the shortest possible duration to avoid serious side effects, particularly liver damage. It is typically prescribed for acute conditions and not intended for chronic use.