Kovex Injection 250mg

Product Name: Kovex  Injection 250mg 

Product Form: Injection

Pack Size: 1's

Manufactured By: Continental Pharmaceuticals

Used For:

• Treatment of serious bacterial infections, especially those caused by gram-negative bacteria, including:

  • Respiratory tract infections (e.g., pneumonia).
  • Urinary tract infections (UTIs).
  • Intra-abdominal infections.
  • Bone and joint infections.
  • Sepsis and bloodstream infections.
  • Skin and soft tissue infections.
  • Tuberculosis (second-line therapy in multidrug-resistant TB).

• Effective against bacteria resistant to other aminoglycosides like gentamicin or tobramycin.

• Neurological:

  • Dizziness
  • Numbness or tingling

• Gastrointestinal:

  • Nausea
  • Vomiting

• Injection Site Reactions:

  • Pain, redness, or swelling

• Rare but Serious:

  • Ototoxicity (hearing damage):
    • Tinnitus (ringing in the ears)
    • Hearing loss (can be permanent)
  • Nephrotoxicity (kidney damage):
    • Reduced urine output
    • Elevated creatinine levels
  • Neuromuscular Blockade:
    • Muscle weakness or respiratory difficulty

1. Kidney Function Monitoring:

   • Regular monitoring is essential as amikacin can cause kidney damage, especially in elderly patients or those with pre-existing kidney issues.

2. Hearing and Balance Tests:

   • Regular audiometry is recommended to detect early signs of ototoxicity, especially with prolonged use.

3. Pregnancy and Breastfeeding:

   • Use with caution during pregnancy as it may cause fetal harm.
   • Consult your doctor before using during breastfeeding.

4. Drug Interactions:

   • Avoid combining with other nephrotoxic or ototoxic drugs (e.g., vancomycin, loop diuretics like furosemide).