Used For:
Type 2 Diabetes: Lowers blood glucose levels by combining the effects of empagliflozin and metformin.
Empagliflozin: Reduces glucose reabsorption in the kidneys, allowing excess sugar to be excreted through urine.
Metformin: Decreases glucose production in the liver and improves insulin sensitivity, helping cells use glucose more effectively.
Side Effects:
Common side effects of this combination include nausea, diarrhea, and abdominal discomfort, particularly with metformin. Empagliflozin may cause urinary tract infections, increased urination, dehydration, and yeast infections. Serious side effects include lactic acidosis (a rare but severe condition caused by metformin), kidney problems, and diabetic ketoacidosis (mainly with empagliflozin).
Precautions:
This combination should be used with caution in patients with kidney or liver problems, as both metformin and empagliflozin are cleared through these organs. Metformin should be avoided in people with severe kidney dysfunction, and empagliflozin may require dose adjustments in those with moderate kidney impairment. It is important to monitor kidney function during treatment. Pregnant or breastfeeding women should consult their doctor before using this combination. This medication should also be used with caution in individuals who are dehydrated or at risk for dehydration.