Avapag Tablets 20mg

Product Description

Product Name: Avapag Tablets 20mg

Product Form: Tablets

Pack Size: 28's

Manufactured By: Everest Pharmaceuticals

Used For:

Avatrombopag is a thrombopoietin receptor agonist used to:

• Treat thrombocytopenia (low platelet count) in adults with chronic liver disease scheduled for a medical procedure to reduce bleeding risks.
• Manage chronic immune thrombocytopenia (ITP): For adults who have had an insufficient response to other treatments.

It works by stimulating platelet production in the bone marrow.

Side Effects:

Common side effects:

• Headache
• Fatigue
• Nausea
• Fever
• Edema (swelling in the hands or feet)
• Increased liver enzymes

Less common side effects:

• Abdominal pain
• Insomnia
• Dizziness
• Musculoskeletal pain

Rare but serious side effects:

• Blood clots (thrombosis), especially in patients with risk factors such as liver disease
• Severe hypersensitivity reactions (rash, swelling, or difficulty breathing)

Precautions:

1. Risk of Thrombosis:

   • Monitor for signs of blood clots, especially in patients with risk factors like advanced liver disease, prolonged immobility, or a history of thromboembolism.

2. Liver Function:

   • Elevated liver enzymes may occur; periodic monitoring is recommended, especially in patients with liver disease.

3. Platelet Monitoring:

   • Platelet counts should be monitored regularly to avoid excessive elevation, which may increase the risk of thrombosis.

4. Pregnancy and Breastfeeding:

   • Use only if clearly needed during pregnancy. Limited data are available, and its safety in breastfeeding is not well established.

5. Drug Interactions:

   • Inform your doctor about all medications, especially anticoagulants, antiplatelet drugs, or drugs affecting liver enzymes.

6. Adjustments for Chronic ITP:

   • Treatment should be tailored based on individual response to minimize long-term risks associated with excessive platelet stimulation.