Amstan Tablets 5mg+80mg

Used For:

• Hypertension (High Blood Pressure): By combining these medications, blood pressure can often be controlled more effectively, helping reduce the risk of cardiovascular events such as heart attacks, strokes, and kidney disease.
• Patients Requiring Dual Therapy: Often prescribed for those who do not achieve adequate blood pressure control with a single medication.
• Angina (Chest Pain): The vasodilating effect of amlodipine can help relieve chest pain by increasing blood flow to the heart.

Side Effects:

• Common Side Effects:
  • Amlodipine: Peripheral edema (swelling, particularly in the legs and ankles), dizziness, headache, and flushing.
  • Valsartan: Dizziness, fatigue, and, in some cases, elevated potassium levels (hyperkalemia).
• Less Common but Serious Side Effects:
  • Amlodipine: Low blood pressure (hypotension), palpitations, and chest pain that worsens, although rare.
  • Valsartan: Kidney dysfunction, hyperkalemia (high potassium levels), and a rare but serious allergic reaction known as angioedema.

Precautions:

• Monitoring Kidney Function and Electrolytes: Especially important for valsartan users, as the medication can increase potassium levels and affect kidney function.
• Pregnancy: Valsartan is contraindicated in pregnancy due to the risk of fetal toxicity. Amlodipine is also generally avoided unless necessary and closely monitored.
• Avoid Grapefruit Juice: Grapefruit can interact with amlodipine, increasing the drug's levels in the blood and intensifying side effects.
• Dehydration: Proper hydration is essential, as dehydration can increase the risk of low blood pressure (especially when standing up, known as postural hypotension).
• Drug Interactions: Caution when combining with other blood pressure medications, potassium supplements, or NSAIDs, as these may alter the effectiveness or increase the side effects.