Amphonex Injection 50mg

Product Description

Product Name: Amphonex Injection 50mg

Product Form: Injection

Pack Size: 1's

Manufactured By: BSV Limited

Used For:

• Treatment of severe fungal infections, including:
  • Systemic mycoses (e.g., candidiasis, aspergillosis, cryptococcosis)
  • Fungal infections in immunocompromised patients (e.g., those with HIV/AIDS or undergoing chemotherapy)
  • Invasive fungal infections affecting organs such as the lungs, kidneys, and brain
  • Meningitis caused by fungi

Side Effects:

• Fever, chills, or rigors during infusion (though less severe than with conventional Amphotericin B)
• Nausea or vomiting
• Abdominal pain
• Headache
• Fatigue
• Electrolyte imbalances (e.g., low potassium, magnesium)
• Liver toxicity or elevated liver enzymes
• Anemia or low red blood cell count
• Rarely, allergic reactions like rash or difficulty breathing

Precautions:

• Liposomal Amphotericin B is generally less nephrotoxic (kidney damage) than conventional Amphotericin B but still requires close monitoring of kidney function and electrolyte levels during treatment.
• Should be administered in a hospital setting where the patient can be monitored for adverse reactions.
• Use cautiously in patients with pre-existing kidney disease, liver impairment, or electrolyte disturbances.
• Hydration is often recommended before and during treatment to minimize kidney damage.
• Not recommended during pregnancy unless the benefits outweigh the risks.
• Avoid concurrent use with nephrotoxic agents unless absolutely necessary, as interactions could increase the risk of kidney damage.
• Monitor for infusion-related reactions, although these are generally milder than with the non-liposomal form.