PHARM-EVO (PVT) LTD.
Opt-D 100 000Iu Capsules
Opt-D 100 000Iu Capsules
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SPECIFICATION
Requires Prescription (YES/NO)
Yes
Generics
Cholecalciferol
Used For
Vitamin D Supplement
How it works
Cholecalciferol (vitamin D3) is formed in the skin under influence of UV rays and metabolized in two hydroxylation steps at first in the liver and then in the kidney tissue into the biological active metabolite 1,25-dihydroxy-cholecalciferol. 1,25-dihydroxy-cholecalciferol is involved fundamentally in the regulation of the calcium and phosphate balance together with parathyroid hormone and calcitonin.
USAGE AND SAFETY
Dosage
Cholecalciferol
Side Effects
Acute symptoms : Arrhythmias, nausea, vomiting, psychic symptoms, and impaired consciousnesses.Chronic symptoms : Polyuria, polydipsia, weight loss, kidney stone formation, nephrocalcinosis, extraosseous calcifications
Drug Interactions
Thiazide diuretics , Phenytoin or barbiturates , Glucocorticoids , Digoxin , Antacids (Magnesium-containing) , Cholestyramine, Colestipol, Mineral Oil.
Indication
1. As dietary supplement for prevention of Vitamin D deficiency in adults and children.2. Prevention of Vitamin D deficiency in high risk patients with malabsorption, certain chronic diseases, disorders of metabolism,drugs or other causes.3. Treatment of vitamin D deficiency states like rickets, osteomalacia and osteoporosis.In all cases calcium supplements must be provided along with Vitamin D supplementation
When not to Use
It may not be used in the following conditions:Hypersensitivity to Cholecalciferol or any of the ingredients of the drug.Hypercalcemia and/or hypercalciuria.It should not be administered to patients : With a tendency towards the formation of kidney stones containing calcium ; With pseudohypoparathyroidism.
PRECAUTIONS
Precaution
If other vitamin D containing drugs are administered, the dosage of Cholecalciferol must be taken into account. Additional administration of vitamin D or calcium should be carried out only under medical monitoring. In such cases the calcium levels in the serum and urine must be supervised.
WARNINGS
Warning 1
It should be administered only with caution to patients with a disturbed renal calcium and phosphate excretion.
Warning 2
In the case of hypercalcemia or reduced kidney function the dosage must be reduced or the therapy discontinued.
Warning 3
It should be administered only with caution to patients suffering from sarcoidosis since the risk of transformation of vitamin D into its active metabolites is increased.
ADDITIONAL INFORMATION
Pregnancy category
Always consult your physician before using any medicine.
Storage (YES/NO)
Store this medicine at room temperature, away from direct light and heat.
